Abstract: Knowledge supply chain management is a systematic and integrated management mode with knowledge innovation as the target and satisfying the needs of users as the start point and destination. Applying knowledge supply chain to carry out knowledge service, library should implement business process reorganization, strengthen the construction of featured collection, establish knowledge exchange mechanism, promote the integration of knowledge supply chain management and improve librarians' professional qualities, so as to establish a set of library-fitting practices. Results showed it was necessary and feasible to introduce that theory of knowledge supply chain into the library.