Abstract: With the development of Internet and cloud computing technology, library service is changingfrom the literature service, information service to knowledge service transformation and development.Through the analysis of interaction mechanism of the college student readers innovation needs and libraryknowledge service transformation, analysis of the multiple factors influencing college student readersinnovation ,describes the chances and challenges facing the transformation of knowledge service strategy,and puts forward strategies of library knowledge service strategic transformation.

Key words: college student readers innovation needs